I predict we get two adventures, one a campaign the other an anthology. Not that I think it will happen, but I think it's time to flip the paradigm and have the longer campaigns be updates of classics and the anthologies be original material. Their track record with these long adventures has been somewhat weak (and the ones considered the best, Curse of Strahd and ToA, and either remakes or heavily influenced by classic adventures). Personally, I'd like to see anthologies of 4-5 shorter adventures, that could be linked, and as additional ones are published a DM can mix and match adventures to form a campaign.
I think there will be two rules books, one a player options book (but I suspect the "Guide to Everything" titles will be replaced for the 2024 era) and one a DM-facing book with monsters and possibly other threats like traps and hazards. I think either book will be a mix of new and updated material, but it's hard to say what the ratio will be--at a guess I'd say 50-60% updated content. I don't necessarily think that will be an ongoing release pace, but I think there is high interest in updated material.
I think we will see a campaign setting release, which may be two books like the FR books this year. I suspect the next setting will be one we have seen before, but given that they are hiring a world builder I think in the future we will see brand new settings.
What that setting will be is hard to say; as much as I love Eberron, I cannot imagine we'll see it again after this year's release. A refresh or Ravenloft, Spelljammer, or Planescape are possibilities, but probably narrow ones given their lukewarm receptions. I also doubt we will see Greyhawk or Dragonlance as they aren't distinct enough from the Realms. Dark Sun would be a contender based on its unique style, but the sensitive subject matter of slavery is a very strong argument against it--unless they did something very unexpected like move the story ahead a century or so, perhaps after a slave revolt. Given the popularity of anime, a modified, culturally updated, renamed Oriental Adventures setting is a possibility--the Realms has changed a lot, but as far as I know there hasn't been much talk about what happened on the Kara-Tur side of the world. Or they could pull some MtG world out (having played Magic like twice in the last 30 years, I have no insight into what such a setting would be).